强光照和黑暗条件下刺参体壁的基因表达差异

参对光照变化非常敏感，研究刺参对光照的分子响应非常重要。本研究应用RNA测序获取了刺参暴露于强光（“强光”）、正常光照（“对照”）和完全黑暗（“黑暗”）环境下体壁的基因表达谱情况，通过“对照”与“黑暗”，“对照”与“强光”和“黑暗”与“强光”的比较，在|log₂ ratio|≥1和FDR≤0.001的标准下分别发现了1161、113和1705个差异表达基因（DEGs）。基因本体分析表明，“cellular process”和“binding”在“生物过程”和“分子功能”类别中的DEGs富集最多，而“cell”和“cell part”在“细胞组分”类别中的DEGs富集最多。将DEGs与Kyoto Encyclopedia基因和基因组数据库上的于214、41和229条通路进行比对，发现了51、2和57条通路分别显著富集。本研究发现的光特异性DEGs可作为深入研究刺参对光照变化的生化适应机制的重要目标基因。     

Galaxy formation: Warm dark matter, missing satellites, and the angular momentum problem

We present warm dark matter (WDM) as a possible solution to the missing satellites and angular momentum problem in galaxy formation and introduce improved initial conditions for numerical simulations of WDM models, which avoid the formation of unphysical haloes found in earlier simulations. There is a hint, that because of that the mass function of satellite haloes has been overestimated so far, pointing to higher values for the WDM particle mass. This revised version was published online in August 2006 with corrections to the Cover Date.     

Can gas dynamics in centres of galaxies reveal orbiting massive black holes?

If supermassive black holes in centres of galaxies form by merging of black hole remnants of massive Population III stars, then there should be a few black holes of mass one or two orders of magnitude smaller than that of the central ones, orbiting around the centre of a typical galaxy. These black holes constitute a weak perturbation in the gravitational potential, which can generate wave phenomena in gas within a disc close to the centre of the galaxy. Here, we show that a single orbiting black hole generates a three-arm spiral pattern in the central gaseous disc. The density excess in the spiral arms in the disc reaches values of 3–12 per cent when the orbiting black hole is about 10 times less massive than the central black hole. Therefore, the observed density pattern in gas can be used as a signature in detecting the most massive orbiting black holes.